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University of Sheffield: Human and Molecular Genetics
Institution | University of Sheffield |
---|---|
Department | Molecular Biology and Biotechnology |
Web | http://www.sheffield.ac.uk |
Study type | Taught |
MSc
Summary
Explore human genetics and develop an understanding of how human genetic diseases are diagnosed clinically at the chromosome and DNA levels.
**Course description**
Designed in collaboration with the NHS: Sheffield Diagnostic Genetics Service, this course is for students who are fascinated by medical genetics.
Through theoretical and hands-on practical skills training you’ll explore human genetics and develop an understanding of how human genetic diseases are diagnosed clinically at the chromosome and DNA levels. You’ll also have opportunities to explore the wider implications of genetics in fields such as genomics, human fertility, stem cells and cancer biology.
As part of your course, we’ll train you in a wide range of exciting, modern laboratory techniques, including CRISPR genome editing, molecular cloning, organism handling, DNA sequence analysis, PCR, SDS-PAGE and western blotting.
The biggest part of your course is the medical genetics laboratory project. Here you’ll spend up to six months undertaking extensive training in advanced laboratory techniques such as human cell culture, microscopy,cytogenetics and qPCR and applying this knowledge to the study and diagnosis of human genetic diseases.
Example research projects include:
Clinical Functional Genomics of human peroxisomal disorders
The role of RNA regulatory proteins in telomere homeostasis and genome stability
Genomic Haemato-Oncology Diagnostics: Improving Patient Outcomes
The role of human ribonucleoproteins (hnRNPs) in the 3D-organisation of the genome
NHS placements
There are opportunities to participate in NHS placements via our collaboration with the Julia Garnham Centre based in the School of Biosciences. The centre provides students with essential experience and training in genetic analysis, upskilling the next generation of genomic scientists and technologists.
After initial training, placement students will work under the supervision of NHS Geneticists from the Sheffield Children's NHS Foundation Trust to prepare cases for NHS Healthcare Scientists to analyse.
Level | RQF Level 7 |
---|---|
Entry requirements | Minimum 2:1 undergraduate honours degree in molecular biology or a related subject (e.g. biochemistry, genetics, biotechnology, microbiology). We also accept medical students who wish to intercalate their studies. We may also consider your application if you do not meet the standard academic requirements but you have relevant professional experience. An interview will be required in this case. We also consider a wide range of international qualifications: Overall IELTS score of 6.5 with a minimum of 6.0 in each component, or equivalent. |
Summary
Explore human genetics and develop an understanding of how human genetic diseases are diagnosed clinically at the chromosome and DNA levels.
**Course description**
Designed in collaboration with the NHS: Sheffield Diagnostic Genetics Service, this course is for students who are fascinated by medical genetics. Through theoretical and hands-on practical skills training you’ll explore human genetics and develop an understanding of how human genetic diseases are diagnosed clinically at the chromosome and DNA levels. You’ll also have opportunities to explore the wider implications of genetics in fields such as human fertility, stem cell biology, organism development and the cellular role of RNA.
As part of your course, we’ll train you in a wide range of exciting, modern laboratory techniques, including CRISPR genome editing, molecular cloning, organism handling, DNA sequence analysis, PCR, SDS-PAGE and western blotting.
The biggest part of your course is the medical genetics laboratory project. Here you’ll spend six months undertaking extensive training in advanced laboratory techniques such as human cell culture, microscopy and cytogenetics before applying this knowledge to the study and diagnosis of human genetic diseases.
Example research projects include:
- Clinical Functional Genomics of human peroxisomal disorders
- Diagnostic FISH for Clinical Genetics: Avoiding unnecessary invasive tests
- The role of human ribonucleoproteins (hnRNPs) in the 3D-organisation of the genome
- Culture adaptation in human lymphoblastoid cell lines: The impact of media supplementation
- Students also have the opportunity for NHS clinical work placements in the Sheffield Diagnostic Genetics Service, which is based in the Sheffield Children’s Hospital NHS Foundation Trust.
Please see our University website for the most up-to-date course information .
Level | RQF Level 7 |
---|---|
Entry requirements | A 2:1 degree or equivalent university qualification in molecular biology or a related subject (eg biochemistry, genetics, biotechnology, and microbiology). We also accept medical students who wish to intercalate their studies. Candidates with professional experience may also be considered following interview. English language requirements: Overall IELTS score of 6.5 with minimum of 6.0 in each component, or equivalent. |
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